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\begin{document}
\title{External Projects and Technology Transfer}
\author{Cristina Vistoli, Barbara Martelli}
\address{INFN CNAF, viale Berti Pichat 6/2 40127 Bologna, Italy} 


\ead{barbara.martelli@cnaf.infn.it}

\begin{abstract}
The main mission of the External Projects and Technology Transfer Unit (PETT) is the coordination of CNAF activities funded by external organization (Region, Italian Ministry of Education, EU) and CNAF Technology Transfer actions. PETT Unit coordinates the INFN Technology Transfer Laboratory in Emilia Romagna (TTLab), accredited to the Emilia Romagna High Technology Network (HTN) since 2015. 
In 2018 TTLab submitted 4 proposals to the POR-FESR Emilia Romagna call, and at the beginning of 2019 three of them were approved and funded: FORTRESS, WE-LIGHT and SmartChain.
In the meantime, the TROPIC project, approved in the former POR-FESR call, continued to run smoothly and the Harmony project started to move from a Proof of Concept phase to the production one.
In its first year of life, the ISO 27001 Information Security Management System (ISMS) had to manage the critical situation originated by the datacenter flood happened at the end of 2017 and it did it successfully, passing the ISO 27001 external audit without any non-conformity. 

\end{abstract}

\section{Introduction}
During 2018 the External Projects and Technology Transfer (PETT) Organizational Unit has
contributed to various projects in the field of computing, communication of science, technology
transfer and education. Some of the most relevant ones are: FiloBlu (POR-FESR Regione
Marche), Opus Facere (MIUR), Emilia Romagna Plan for high
competencies in Research Technology Transfer and Entrepreneurship, OPEN-NEXT and TROPIC(POR-FESR
2014-2020), Harmony. Great effort has been put on the
start up phase of the new Technology Transfer Laboratory which put together heterogeneous
competencies (physics, computing, mechanics and electronics) from Emilia Romagna INFN
Sections and Centers (Bologna, Ferrara and CNAF) in order to promote the transfer of INFN
know-how toward regional enterprises. In 2017 we concluded an activity finalized to
the ISO-27001 certification of a subset of the INFN Tier1 resources. This is required in order
to store and manage private and sensitive personal data and could open new opportunities of
exploitation of the Tier1 resources in the near future.

\section{The TROPIC project}
TTLab is coordinating the TROPIC project (Target for Radioisotope Production via anti-Channelling) in a consortium with COMECER and Biomeccanica Srl.
The project is part of the European Regional Development Plan POR-FESR Axis 1, Research and Innovation 2014-2020 of the Emilia-Romagna region.  Axis 1 aims at strengthening the regional network of research and technology transfer to companies with the purpose of increasing the ability to bring innovative solutions and products to the market. Through collaborations with researchers, it promotes innovation paths in the strategic areas of the regional production system and strengthens the high-tech network.
The TROPIC project intends to explore a new radioisotope production method through the irradiation of solid targets in which a quantum effect called anti-channelling is exploited. Thanks to this effect, the probability of impact of the particle emitted by the accelerator on a crystalline matrix is much higher than the same dynamic but with a traditional amorphous solid target. This leads to an increase in the yield of nuclear bombardment and thus produces the desired isotope in larger quantities. The project intends to evaluate how much it is possible to save in terms of cost of the enriched material and how much the reaction yield grows in this particular configuration of the target. The ultimate goal is to make the production of these isotopes, extremely interesting from a diagnostic and therapeutic point of view, easier and less expensive.
The theoretical research activity has already produced various results published in the past years.  The next step will be the experimental test and the realisation of the first prototype.

\section{Summer Students and CNAF Log Analysis}
....

\section{The HARMONY Alliance}
The HARMONY project (Healthcare alliance for resourceful medicines offensive against neoplasms in hematology) \cite{harmony} is part of IMI’s Big Data for Better Outcomes programme, which aims to facilitate the use of diverse data sources to deliver results that reflect health outcomes of treatments that are meaningful for patients, clinicians, regulators, researchers, healthcare decision-makers, and others.

Blood cancers, or haematologic cancers (e.g. leukaemia, lymphoma and myeloma), affect the production and function of blood cells and account for about one third of cancer cases in children and about one third of cancer deaths. As many blood cancers are rare, and healthcare practice varies across EU, a lack of data on relevant outcomes represents a challenge for clinicians, researchers, and decision-makers alike. The HARMONY project aims to use big data to deliver information that will help to improve the care of patients with these diseases. Specifically, the project will gather together, integrate and analyse anonymous patient data from a number of high quality sources. This will help the team to define clinical endpoints and outcomes for these diseases that are recognised by all key stakeholders. Meanwhile the project’s data sharing platform will facilitate and improve decision making for policy makers and clinicians alike to help them to give the right treatment to the right patient at the right time. More broadly, the project will result in a pan-European network of stakeholders with expertise in this disease area.
TTLab is involved as Linked Third Party of University of Bologna and is in charge of providing and managing the Harmony Big Data Platform Hosting.

\section{Other regional activities}
In 2018, as industrial research lab of the Emilia Romagna High Technology Network \cite{htn}, TTLab carried out a number of activities in order to strengthen the link between research and industry sector. 

In 2018 TTLab kept on contributing in the following Emilia Romagna Clust-ERs: 
\begin{itemize}
\item[--]INNOVATE (ICT): focused on the role of digital technologies as a means for innovate services in a global context and to emphasize their transformative power of the economy and society.
\item[--]AGRIFOOD: covers the whole “from farm to fork” value chain, starting from the farmed produce all the way to the consumers’ plates, it includes ICT systems, equipment and machineries, transformation and packaging plants, logistics and food by-products and waste valorization.
\item[--]CREATE: aims to improve the innovation in the culture and creative industries sector
\item[--]HEALTH: focused on health related topics like biomed, pharmaceutical and omics sciences, smart and active living. In Emilia-Romagna there is the most important medtech district in Europe and regional policies encourage local research actors to team-up with private companies in order to maximize innovation. 
\item[--]MECH: focused on the mechatronics and motor sector. A number of worldwide famous brands both in the automotive and in the mechanical sector are located in the region. These companies are at the cutting edge of a corporate system and can take advantage of technologies developed by our research teams. 
\item[--] BUILD: supports the innovation system in the building and construction field.
\end{itemize}
Clust-ERs are recognised Associations, formed in accordance with articles 14-42 of the Italian Civil Code. Clust-ER Associations are communities of public and private bodies (research centres, businesses, training bodies) that share ideas, skills, tools, and resources to support the competitiveness of the most important production systems in Emilia-Romagna. In these Clust-ERs, research laboratories and centres for innovation belonging to the High Technology Network team up with the business system and the higher education system to make up the inter-disciplinary critical mass necessary to multiply opportunities and develop strategic projects with a high regional impact. Main objectives of Clust-ERs are: to maximise the opportunities for participating in European programmes and international research and innovation networks, to forge synergies and set up coordinated and stable networks and connections with other public/private agglomerations operating in the same sectors at national and European level, to encourage and support the development and creation of initiatives in higher education and the development of human resources and to support the development of new research infrastructures.
TTLab is part of the National Cluster ``Intelligent Factories'': an association that includes large and medium-small companies, universities and research centres, company associations and other stakeholders active in the advanced manufacturing sector. The association is recognized by MIUR as a driver of sustainable economic growth in all the regions of the national economic system, as it fosters the innovation and specialization of Italian manufacturing systems. The mission of CFI is to increase the competitiveness of the italian maufacturing industry through the design and implementation of a number of research projects for the development of new enabling technologies; to maintain and develop advanced skill in Italian manufacturing; to increase Italian companies access to national and international funds; to support entrepreneurship and company growth through the involvement of private investors. 

TTLab particapates to the project Opus Facere (Lab for Employability) \cite{opusfacere} with a course about Cosmic Rays Data Analysis, on the EEE \cite{eee} experiment data, where students of the fifth year of secondary school can understand and practice the job of data scientist and physicist. 

In 2018 TTLab started the activities founded by the Regional Plan for High Competencies for Research, Technology Transfer and Entrepreneurship (5 research grants) for industrial research activities in different areas: models and algorithms for genome sequencing analysis, geospatial data access and processing services, big data analisys of physical, atrophysical and aerospatial data, big data analysis for smart cities. In particular, the research grants activated are: 
\begin{itemize}
\item[--]Big Data Analysis: algorithms and models for the analysis of nucleic acid sequencing data  - partner CIG/Unibo
\item[--]Big Data management: services for accessing and processing geospatial data in the era of Big Data – Industrial  partner MEEO s.r.l Meteorological Enviromental Earth Observation http://www.meeo.it/wp/
\item[--]Big Data management: the analysis of data in the field of physics, astrophysics and space science industrial partner VEM Sistemi  S.p.A https://vem.com/en/
\item[--]Big Data management: Big Data in Smart Cities Industrial partner Filippetti S.p.A https://www.filippetti.it/en/
\end{itemize}
  
Finally, PETT coordinated the participation of INFN to the BI-REX (Big data Innovation and Research Excellence) Competence Center and actively contributed to the proposal. The BI-REX Competence Center is a project funded by the Ministry of Economic Development in the scope of Industry-4.0 plan. It involves 61 public and private partner, among which all Universities and Research Agencies in the Emilia Romagna region and a number of enterprises of all sizes (multinationals, large and SME). 

\section{Conclusions}
In 2018 the External Projects and Technology Transfer group consolidated its collaboration with the research and innovation regional system participating and contributing to many initiatives aimed at creating a strong partnership between the research and industry sectors. 

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